Stenabolic SR9009

Stenabolic (SR9009) is a synthetic agonist of the nuclear receptor REV-ERBα. It has been studied in various non-clinical research settings for its potential role in regulating circadian rhythms, metabolic activity, lipid profiles, and mitochondrial energy utilization. SR9009’s influence on gene expression makes it of interest in studies related to metabolism, endurance, and inflammation.

Research Focus Areas

• Metabolic Regulation
  SR9009 has been shown to modulate lipid and glucose metabolism via REV-ERBα activation, influencing the expression of genes involved in fat storage, fatty acid oxidation, and plasma cholesterol levels.
• Circadian Rhythm Modulation
  SR9009 impacts the expression of core clock genes, potentially altering circadian-related behavior and metabolism. These findings support its utility in studies on biological rhythm regulation.
• Mitochondrial Activity and Energy Expenditure
  Research suggests(https://www.nature.com/articles/nature11030) SR9009 increases mitochondrial biogenesis and enhances oxidative metabolism in skeletal muscle, potentially increasing overall energy expenditure.

Potential Observations in Research

• Altered Sleep-Wake Markers
  Some studies have reported changes in wakefulness duration and suppression of REM sleep following exposure to SR9009.
• Modulation of Inflammatory Pathways
  SR9009 has been observed to reduce the expression of pro-inflammatory cytokines and proteins, suggesting possible anti-inflammatory activity in test environments.
• Lipid Profile Shifts
  Data indicate SR9009 may lower plasma triglycerides and total cholesterol levels during metabolic studies.

Handling and Dosage Information

SR9009 is typically available in research concentrations ranging from 10–30 mg/mL. The volume and delivery method should be selected according to each study’s requirements. Sublingual administration has been explored in certain settings for absorption analysis but is not required in all protocols.

• Store in a cool, dry place away from light
• Use precision instruments for measurement
• Follow laboratory safety protocols during handling

Important Notice:
This product is intended for laboratory research use only. It is not intended for human consumption, medical, veterinary, or household use. Keep out of reach of children.

FDA Disclaimer: The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease. All products are for laboratory developmental research USE ONLY. Products are not for human consumption.

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