Myostine YK11

YK11, also known as Myostine, is a synthetic steroidal Selective Androgen Receptor Modulator (SARM) that has been studied for its potential to influence muscle differentiation and bone formation. It exhibits partial agonist activity at the androgen receptor (AR) and has been observed to upregulate follistatin expression, a known inhibitor of myostatin, which is a negative regulator of muscle growth.​

Research Focus Areas

• Myogenic Differentiation and Follistatin Expression
  YK11 has been shown to promote myogenic differentiation by increasing follistatin levels, thereby potentially inhibiting myostatin activity. This mechanism suggests a role in muscle cell development and growth.
• Osteoblastic Activity and Bone Formation
  Studies indicate that YK11 can enhance osteoblastic proliferation and differentiation, leading to increased markers of bone formation such as osteocalcin and alkaline phosphatase activity. These effects are mediated through AR signaling pathways.
• Selective Androgen Receptor Modulation
  As a partial AR agonist, YK11 demonstrates selective activation of androgen-responsive genes, which may result in anabolic effects on muscle and bone tissues without significant androgenic side effects.

Potential Observations in Research

• Oxidative Stress and Mitochondrial Function
  Investigations have reported that YK11 may induce oxidative stress and affect mitochondrial function in certain cell types, highlighting the need for further studies on its safety profile.
• Metabolic Pathways and Biotransformation
  Research into the metabolism of YK11 has identified various metabolites, suggesting complex biotransformation pathways that warrant additional exploration.

Handling and Dosage Information

YK11 is typically prepared at concentrations of 5 to 30 mg/mL, with volume and administration method determined by the specific research protocol. Sublingual or split-dose strategies may be explored, though they are not required. The compound should be stored in a cool, dry place, protected from light, and sealed when not in use. Accurate handling requires calibrated equipment and adherence to standard lab safety procedures. 

Important Notice:
This product is intended for laboratory research use only. It is not intended for human consumption, medical, veterinary, or household use. Keep out of reach of children.

FDA Disclaimer: The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease. All products are for laboratory developmental research USE ONLY. Products are not for human consumption.

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